The 63 potentially amoeba-specific gene families are represented by 78 genes in D. discoideum. The genes were run using BLASTP against the NCBI nr database (D. discoideum and E. histolytica genes were removed prior to running the analyses). Genes in the same family are grouped together and assigned with the same background color, either white or gray.

D. discoideum genes in selected families (click to view them on dictyBase) Putative function suggested by BLASTP against nr (click to view the raw report) Mutants (click to view them on dictyensembl)
Genes that only have orthologs in other amoebae
DDB0186845 cigB
DDB0169085 cigB REMI_mutant
DDB0214810 actin-binding protein
Genes that do not have orthologs in nr
DDB0204779 Unknown
DDB0169210 Unknown
DDB0217083 histidine kinase REMI_mutant
DDB0217915 histidine kinase
DDB0167801 putative lipase
DDB0202946 Unknown
DDB0205029 Unknown
DDB0186030 Unknown
DDB0186991 cudA (transcription factor)
DDB0191385 cudA (transcription factor) REMI_mutant
DDB0218432 Unknown
DDB0218881 Unknown
DDB0186473 Unknown
DDB0186475 Unknown
DDB0231576 prespore-specific
DDB0187694 Unknown
DDB0192053 Unknown
DDB0218228 Unknown
DDB0220096 bZIP transcription factor
DDB0187415 Unknown
DDB0168763 Unknown
DDB0219313 prespore-specific
DDB0203241 Unknown
DDB0216772 Unknown
DDB0186133 Unknown
DDB0187995 Unknown
DDB0189619 Unknown
DDB0191013 Unknown
DDB0188019 Unknown
DDB0202283 Unknown
DDB0202973 Unknown
DDB0185655 Unknown
DDB0204282 Unknown
DDB0190831 Unknown
DDB0191884 Unknown
DDB0202188 Unknown
DDB0205163 Unknown
DDB0205268 Unknown
DDB0214957 cbpP (calcium binding protein)
DDB0184280 Unknown
DDB0217976 Unknown
DDB0229797 Unknown
DDB0186341 Unknown
DDB0188978 Unknown
DDB0189253 Unknown
DDB0189388 Unknown
DDB0189538 Unknown
Genes that share some domains with entries in nr
DDB0168925 sphingomyelinase
DDB0187737 sphingomyelinase
DDB0169405 Hypothetical
DDB0205190 SAM-dependent methyltransferases
DDB0231234 Hypothetical
DDB0203824 Hypothetical
DDB0202532 Hypothetical
Genes that have orthologs in nr
DDB0230169 uridine phosphorylase
DDB0185607 Hypothetical
DDB0218014 Hypothetical
DDB0186645 Hypothetical
DDB0186647 Hypothetical
DDB0186648 Hypothetical
DDB0186649 Hypothetical
DDB0187572 endoglucanase
DDB0202584 endoglucanase
DDB0184284 type I restriction-modification system
DDB0218043 type I restriction-modification system
DDB0231551 glutamine synthase
DDB0192000 Hypothetical
DDB0169170 glycerate kinase
DDB0217577 Hypothetical REMI_mutant
DDB0187273 phosphoesterase
DDB0204031 tyrosine phenol-lyase
DDB0230112 deoxycytidine deaminase
DDB0168966 Hypothetical
DDB0217632 Hypothetical
DDB0185789 oxidoreductase